Actions: Decrease the release of glucose by the liver.
Increase sensitivity of the cells to insulin.
Treatment of type 2 diabetes mellitus
Nausea, vomiting, anorexia,, abdominal cramps, and flatulence,
severe side effects:
malaise, respiratory distress, and hypotension
1. chlorpropaminde (Diabinese)
2. Glimepiride (amaryl)
3. Glipizide (Glucotrol)
4. Glyburide (Diabeta, Micronase)
5. Tolazamice (Toninase)
6. Tolbutaminde (Orinase)
patients that are allergic to sulfonilureas or sulfur shouldn’t take these group of medications.
1. Repaglinide (Prandin)
2. Nateglinide (Starlix)
Stimulate release of insulin form beta cells of pancreas
Avandia and Actos are very popular in these group
* Act as insulin sensitizers and are believed to reduce the amount of insulin needed while improving blood sugar control
* Increase sensitivity of muscle and fat tissue to insulin.
1. Acarbose ( Precose)
2. Miglitol ( Glyset)
fast acting insulin the new formula can be injected 15 minutes before meal
Humilin N insulin starts to peak in 4 hours. the nurse should be monitor for hypoglycemia reaction
the patient needs to alert the nurse for hypoglycemic reaction
oral hypoglycemic are compounds that stimulate the beta cells in the pancreas to increase insulin release
not straight from the refrigerator to prevent lipodistrophy.