3. Assistance in Movement
4. Mineral Homeostasis (Storage and Release)
5. Blood cell production
6. Triglyceride Storage
1. The initial formation of bones in an embryo and fetus.
2. The growth of bones during infancy, childhood, and adolescence until their adult size is reached.
3. The remodelling of bone (replacement of old bone tissue by new bone tissue throughout life).
4. The repair of fractures (breaks in bones) throughout life.
1. Development of ossification centre.
3. Formation of Trabeculae.
4. Development of the Periosteum.
1. Development of the Cartilage Model.
2. Growth of the Cartilage Model.
3. Development of the primary ossification center.
4. Development of the Medullary (Marrow) Cavity.
5. Development of the Secondary Ossification Centers.
6. Formation of Articular Cartilage and the Epiphyseal (growth) Plate.
1. Interstitial growth of cartilage on the epiphyseal side of the epiphyseal plate
2. Replacement of cartilage on the diaphyseal side of the epiphyseal plate with the bone by endochondral ossification.
1. Zone of resting cartilage
2. Zone of perforating cartilage
3. Zone of hypertrophic cartilage
4. Zone of calcified cartilage
2. Eventually, the ridges fold together and fuse, and the groove becomes a tunnel that encloses the blood vessel. The former periosteum now becomes the endosteum that lines the tunnel.
3. Osteoblasts in the endosteum deposit bone extracellular matrix, forming new concentric lamellae. The formation of additional concentric lamellae proceeds inward toward the periosteal blood vessel. In this way, the tunnel fills in, and a new osteon is created.
4. As an asteon is forming, osteoblasts under the periosteum deposit new circumferential lamellae, further increasing the thickness of the bone. As additional periosteal blood vessels become enclosed as in step 1, the growth process continues.
1. Reactive Phase
2. Reparative Phase: Fibrocartilage callus formation and bony callus formation
3. Bone remodelling phase