Cancer Drugs Pharmacology ORU nursing 2012

Cytoxan (cyclophsophamide)
aklylating agent, hemorrhagic cystitis (must empty bladder frequently, pulmonary toxicity, keep hydrated

Platin, cumulative kidney disfunction, hearing loss, hold if creatine < 1.5, vesicant (tissue necrosis)

Platin, dose based on creatine, hypersensitivity after 7 doses

antimetabolites, mucositis (ice chips), hair loss, photosensitvity

Methotraxate (MTX)
antimetabolites, neurotoxicity, mucositis, renal/liver toxic, photosensitivity

antineoplastic antibiotic, pulmonary fibrosis, hair loss, hyperpigmentation, fever/chills

Doxorubicin (adriamy)
antineoplastic antibiotic, cumulative cardiac toxicity, mucositis, hair loss, red urine

mitotic inhibitor

yew tree, allergic reactions, peripheral neuropathy

plant alkaloids, numbness, reflex loss, constipation, hair loss, jaw pain

plant alkaloids, numbness, BMS, loss of reflex, constipation, hair loss

Hormonal therapy

Methylprednisolone (Solu-medrol)
Hormonal Therapy

Hormonal Therapy, myeloma, lymphoma

Antiestrogen agent

Aromatase inhibitor (arimidex)
antiestrogen agent

Triptorelin (Telstar)
anti androgenic

anti androgenic

anti androgenic (1-3 mo)

Hormone therapy, synthetic progestin, manage anorexia, weight loss in AIDs

inhibit cellular replication, fever/chills, hep C, kaposi sarcoma, leukemia, depression suicide

Biological therapy, B and T cell recruitment, Melanoma, 3rd space of fluid (Albumin, dehydrated)

Epogen, Procrit, Aranesp
RBC stimulator

Neupogen, Neulasta
WMB stimulator

Reclast, Actonel, Fosamax, Boniva
Supportive drugs

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Pneumo 1 A 28-year-old man is evaluated for a 6-month history of episodic dyspnea, cough, and wheezing. As a child, he had asthma and allergies, but he has been asymptomatic since his early teenage years. His recent symptoms started after …

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